Google Chrome. I kind-of hate it (many of the addons I love in Firefox either suck or don't exist). Kind-of love it (way-cool offline saving/editing of docs). It just depends on what we're talking about.
You can easily create shortcuts on your Desktop, assign "speed keys" for opening, and I like the window that gets opened!
Target, change the stuff beginning with
–app=[document website URL]
–app-idand that's not a typo
Shortcut keydo as you normally do to set a speed key (e.g. pressing "x" will result in Ctrl+Alt+X or you can modify it to use Shift+Ctrl or Shift+Alt plus a key)